human leukocyte antigen profile of two ethnic groups in southeast of iran

this study was performed to determine the genetic diversity of hla class i and ii alleles among two ethnic groups in southeastern iran. hla profiles were determined in 71 iranian populations (41 zaboli and 30 baloch). the frequencies of hla-a02 (p=0.017), -cw4 (p=0.003), and -dr8 (p=0.025) in the zaboli populations were significantly higher than that in baloch ethnic group. in contrast, the frequency of hla-a23 allele was more frequent in baloch than zaboli (p=0.020). this report represents an important resource for investigators in the fields of transplantation immunology and population genetics from widely dispersed areas of iran.